Valentia Analytical – Analytical Lab Born in GMP


Ultra-High Performance Liquid Chromatography (UHPLC) is a core competence at Valentia Analytical enabling use of sub-2 micron particle columns to achieve maximal resolution.  This is in comparison to traditional high performance liquid chromatographic systems that could not.   That being said, methods may come in requiring the specific use of HPLC.  The specific system we have enables use of either mode, in UHPLC or HPLC.  Collective years of expertise have been forged with different chromatographic modes including reversed-phase, size-exclusion, ion-exchange, and affinity chromatography.


Active Pharmaceutical Ingredient (API) content, purity, impurity; raw material identification, drug content, drug load, characterization of degradation products, peptide mapping of proteins for identity.

Reversed-Phase Chromatography


Plasmid DNA topoisomeric homogeneity for open chain, supercoiled, and linear forms; protein charge heterogeneity.

Ion Exchange Chromatography


Protein aggregation, Protein degradation, Plasmid DNA multimer analysis.

Size Exclusion Chromatography

B-cell and antibodies, 3D illustration. Principles of immunity

IgG titer content using protein A.

HPLC Affinity Chromatography


Drug release testing per USP<724> using USP Apparatus 2

Drug Release

Hand holding test tube with pH indicator comparing color to scale

Compendial testing per USP <791> pH, EP 2.2.2. <Degree of Coloration of Liquids>

Compendial Testing