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Pharmaceutical manufacturers have the responsibility to offer the market safe and reliable drug products. Compendial testing makes it possible for healthcare professionals, pharma businesses, and regulatory entities to ensure that only the best medicines reach the hands of patients.   What is compendial testing? Compendial testing refers to a series of principles and procedures devised…

Since its invention in the 1950s, size-exclusion chromatography has been widely used for the analysis of proteins and other water-soluble polymers. Size-exclusion chromatography has many applications in modern science, as it is one of the main tools used by researchers to separate molecules.   What is size exclusion chromatography? Also known as molecular sieve chromatography,…

Chromatography has seen several developments throughout the 20th century. The term chromatography comes from the Greek words chroma, meaning “color”, and graphos, which means “to write”. This is because the technique was primarily used to separate plant pigments such as chlorophyll during its first years of existence. New chromatography techniques have been developed since then.…

Chromatography is one of the most important techniques in the study of biological molecules. Thanks to chromatographic separation techniques, the unique properties of proteins, amino acids, and other molecules can be isolated, analyzed, and used to create new scientific developments.   What is ion exchange chromatography? Ion exchange high-performance liquid chromatography is a scientific analysis…

Reversed-phase high-performance liquid chromatography has become one of the most popular methods to separate molecules in the pharmaceutical industry. In recent years, reversed-phase chromatography has become the industry standard for precise and reliable proteomics analysis.   What is reversed-phase chromatography?  Reversed-phase chromatography is a chemical analysis technique used to drive the separation process of a…

ADCs are a novel and impressive clinical development. ADC characterization allows scientists and drug manufacturers to understand the physical and chemical properties of ADCs, improving their creation methods and development.  What is ADC in immunology? Antibody-drug conjugates (ADCs) are biopharmaceutical drug products designed for the treatment of various forms of cancer. The molecular buildup of…

Genetic engineering has revolutionized the way scientists think about diseases. New technological advancements like gene editing have allowed medical researchers to alter the composition of DNA, a groundbreaking technique that has led to the development of gene therapy.  What is gene therapy? Gene therapy is a novel treatment method that uses genetically engineered medicine to…

The cure for cancer has long been sought after by modern medicine. While traditional approaches to treating cancer have often produced unsuccessful results, antibody-drug conjugates promise to change that reality.   What are antibody-drug conjugates? Antibody-drug conjugates (ADCs) are biopharmaceutical drug products. ADCs are bioconjugates that possess a complex chemical composition. The molecular structure of…